Showing posts with label DIAGNOSIS OF COVID-19 LAB. Show all posts
Showing posts with label DIAGNOSIS OF COVID-19 LAB. Show all posts

Saturday, March 21, 2020

‏LABORATORY MARKERS IN COVID-19

‏LABORATORY MARKERS IN COVID-19 PATIENTS :microscope::syringe:
‏MOST FREQUENT
‏Decrease lymphocyte count
‏Decrease albumin
‏Decrease hemoglobin levels
‏Increase C-reactive protein (CRP)
‏Increase Erythrocyte Sedimentation Rate (ESR)
‏Increase Lactate Dehydrogenase (LDH)
‏Increase D-dimer

- Deaths from Covid-19 are due to (1) cytokine storm syndrome and (2) fulminant myocarditis.

- During a cytokine storm, an excessive immune response ravages healthy lung tissue, leading to acute respiratory distress and multi-organ failure.

- All Covid-19 patients sick enough for hospitalization should be given a serum ferritin blood test.

- Elevated serum ferritin values are a good first screening tool for the possibility of a cytokine storm syndrome in sick patients with high fevers.

- Treating Covid-19 infected patients with cytokine storm syndrome with IL-6 blockade (tocilizumab) has recently been reported in China with successful outcomes.

- Fulminant myocarditis :heart: has also been reported in patients with Covid-19

- Fulminant myocarditis is primarily caused by infection with viruses. It arises quickly, progresses rapidly, and may lead to severe heart failure or circulatory failure presenting as rapid-onset hypotension and cardiogenic shock, with mortality rates as high as 50%–70%.

- Physicians should pay attention not only to the symptoms of respiratory dysfunction but also the symptoms of cardiac injury.


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‏Source: Lippi G, Plebiani M. Laboratory
abnormalities in patient with COVID-19 infection. Clin Chem Lab Med. 2020 Mar 3. doi: 10.1515/cclm-2020-0198 Covid-19 🦠 Update:*
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